Browsing by Author "Pinedo Soria, Antony"

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Asociación entre la función renal y la severidad en accidente ofídico en el Hospital II-2 Santa Gema de Yurimaguas, 2023-2024
(Universidad Nacional de San Martín. Fondo Editorial, 2025-07-10) Pinedo Soria, Antony; Sánchez Dávila, Keller
Introducción: El envenenamiento ofídico es un grave problema de salud pública global, con alta incidencia en la Amazonía peruana. En 2023, Perú registró 2,210 casos, concentrándose el 49.8% en Loreto y San Martín. El género Bothrops es el principal causante, provocando desde síntomas locales hasta complicaciones sistémicas como hemorragias y lesión renal aguda (LRA). Objetivo: Determinar la asociación entre la función renal y los grados de severidad en el accidente ofídico en el Hospital II-2 Santa Gema de Yurimaguas, durante el periodo 2023-2024. Materiales y Métodos: Se realizó un estudio básico, observacional y correlacional, con un diseño retrospectivo basado en el análisis de expedientes clínicos. La población de estudio estuvo conformada por pacientes atendidos por accidentes ofídicos en el Hospital II-2 Santa Gema de Yurimaguas entre 2023 y 2024. La muestra incluyó 162 pacientes, seleccionados mediante muestreo no probabilístico por conveniencia, que cumplieron con los criterios de elegibilidad. Resultados: Los resultados confirmaron que los trabajadores agrícolas jóvenes masculinos son una población vulnerable. Se estableció una asociación significativa y directa entre la progresión de la LRA y el aumento de la severidad del envenenamiento. Los parámetros de función renal se identificaron como biomarcadores pronósticos cruciales. Aunque las complicaciones locales fueron frecuentes, la LRA, aunque menos común, se correlacionó con envenenamientos más graves, mostrando una relación dosis-respuesta. Conclusiones: existe una asociación directa y significativa entre la progresión de la LRA y la severidad del envenenamiento ofídico, lo que convierte la función renal en un biomarcador pronóstico vital. La detección y el tratamiento temprano de la LRA son esenciales para reducir la morbilidad y mortalidad, ya que la disfunción renal es un factor de riesgo independiente en estos accidentes.
COVID-19 in Latin America and the Caribbean: what is known about the status of school reopening?
(2021-06) Fernandez-Guzman, Daniel; Sangster-Carrasco, Lucero; Pinedo Soria, Antony
Since December 2019, the world has been facing a rapid increase in cases and deaths from the new coronavirus (COVID-19), forcing a response from countries all over the world to stop its transmission. Thus, at the beginning of April, 172 nations closed their schools, affecting >84.8% (~1484 million) of students enrolled worldwide, aiming to reduce the exposure to the virus, a social measure previously used to control the H1N1 influenza pandemic. It is difficult to assess the impact of schools closures on the incidence and mortality from COVID-19, given that it is not easy to carry out experimental studies, there is no scientific support confirms its effectiveness. However, during the influenza outbreaks, this strategy turned out to be a potentially useful intervention, despite not being able to determine the optimal moment to start and end this strategy, because of the concomitant use of other measures during the influenza outbreak; however, in mathematical models, where the school closure was considered as an isolated measure, a reduction between 2 and 4% of the total deaths was calculated during the virus outbreak.
Level of Knowledge Regarding Mpox among Peruvian Physicians during the 2022 Outbreak: A Cross-Sectional Study
(2023-01) Gonzales-Zamora, Jose A.; Soriano-Moreno, David R.; Soriano-Moreno, Anderson N.; Ponce-Rosas, Linda; Sangster-Carrasco, Lucero; De-Los-Rios-Pinto, Abraham; Benito-Vargas, Raysa M.; Murrieta-Ruiz, Valentina; Morocho-Alburqueque, Noelia; Caira-Chuquineyra, Brenda; Fernandez-Guzman, Daniel; Ccami-Bernal, Fabricio; Quispe-Vicuña, Carlos; Alarcon-Parra, Mariano; Pinedo Soria, Antony; Alave, Jorge
Introduction: Due to the high incidence of mpox in Peru and the poor knowledge about this disease among healthcare workers in non-endemic countries, it is crucial to determine the knowledge status of Peruvian physicians. Methodology: We conducted an analytical cross-sectional study based on an online survey from August to September 2022. Physicians who had a medical license and lived and practiced medicine in Peru were included. To evaluate the factors associated with a higher level of knowledge, we used crude (cPR) and adjusted (aPR) prevalence ratios with 95% confidence intervals (95% CI) using Poisson regression. Results: We included 463 physicians. The mean age was 36.6 (SD: 10.3) years, and most were male (58.1%). Regarding knowledge, the median knowledge score was 14 [IQR: 13 to 15] out of 17 points. In terms of knowledge gaps, only 60.7% of the participants knew that there was an FDA-approved vaccine for mpox, 49.0% of participants knew about mpox proctitis and 33.3% acknowledged that it could be transmitted by the bite of an infected rodent. We found that taking care of patients with mpox (aPR: 1.39; 95% CI: 1.13 to 1.72) was associated with higher knowledge (>p50), while living in the eastern macro-region (aPR: 0.62; 95% CI: 0.42 to 0.93) was associated with lower knowledge (≤p50). Conclusions: Our study showed a high level of knowledge about mpox among Peruvian physicians. However, educational campaigns may be necessary, especially for physicians from the eastern region and those who do not have clinical experience with mpox.
Problematic internet use associated with symptomatic dry eye disease in medical students from Peru
(2021-10) Condori- Meza, I. Benjamin; Dávila-Cabanillas, L. Alessandra; Challapa-Mamani, Mabel R.; Pinedo Soria, Antony; Torres, Renato R.; Yalle, Joel; Rojas-Humpire, Ricardo; Huancahuire-Vega, Salomón
Purpose: Dry eye is a multifactorial ocular surface disease (DED) characterized by a loss of tear film homeostasis, which is widely associated with alterations in mental health. Problematic internet use (PIU) is defined as the feeling of concern about using this tool irresistibly, for longer periods than usual, accompanied by anguish that results from not doing so without reaching mania or hypomania behaviors. Both PIU and DED present a theoretical link; however, there are no published studies that report its relationship with problematic internet use. Therefore, this study aims to determine the association between PIU and symptomatic DED in Peruvian medical students. Patients and Methods: Analytical cross-sectional study that included human medical students from Peru. For the measurement of main variables, the Ocular Surface Disease Index (OSDI) and the Internet Addiction Test (IAT) were used. To study their relationship, the Poisson regression analysis was used, we consider a p-value <0.05 as significant. Results: Data from 844 medical students were analyzed, 35.7% male and 64.3% female, with an average age of 21.8 ± 3.3 years. Likewise, the prevalence of symptomatic DED was 70.9%, and the internet’s controlled use was 85.3%. In the analysis adjusted for symptomatic DED, the men showed significant differences in the controlled use of the internet (p <0.003), of which those who had PIU, 50% had severe symptomatic DED, as well as 80% of those addicted to the internet. The adjusted model showed that the PIU increases the prevalence of symptomatic DED in men (PR = 1.17, 95% CI: 1.06–1.29); however, in women, no association was found between both variables. Conclusion: PIU and symptomatic DED showed a significant association in male medical students from Peru.